Reactome

Reactome - a curated knowledgebase of biological pathways

Apoptosis	Axon guidance	Biological oxidations	Botulinum neurotoxicity
Cell junction organization	Cell Cycle Checkpoints	Cell Cycle, Mitotic	DNA Repair
DNA Replication	Diabetes pathways	Electron Transport Chain	Gap junction trafficking and regulation
Gene Expression	HIV Infection	Hemostasis	Influenza Infection
Integration of energy metabolism	Integrin cell surface interactions	Metabolism of lipids and lipoproteins	Membrane Trafficking
Metabolism of amino acids	Metabolism of carbohydrates	Metabolism of mRNA	Metabolism of nitric oxide
Metabolism of non-coding RNA	Metabolism of polyamines	Metabolism of proteins	Metabolism of vitamins and cofactors
Muscle contraction	Metabolism of nucleotides	Metabolism of porphyrins	Pyruvate metabolism and TCA cycle
Regulation of beta-cell development	Regulatory RNA pathways	Signaling by BMP	Signaling by EGFR
Signaling by FGFR	Signaling by GPCR	Signaling by PDGF	Signaling in Immune system
Signaling by Insulin receptor	Signalling by NGF	Signaling by Notch	Opioid Signalling
Signaling by Rho GTPases	Signaling by TGF beta	Signaling by VEGF	Signaling by Wnt
Synaptic Transmission	Telomere Maintenance	Transcription	Transmembrane transport of small molecules
mRNA Processing

About Reactome		News and Notes
REACTOME is a free, online, open-source, curated pathway database encompassing many areas of human biology. Information is authored by expert biological researchers, maintained by the Reactome editorial staff and cross-referenced to the NCBI Entrez Gene, Ensembl and UniProt databases, the UCSC and HapMap Genome Browsers, the KEGG Compound and ChEBI small molecule databases, PubMed, and GO. The curated human data are used to infer orthologous events in 22 non-human species including mouse, rat, chicken, puffer fish, worm, fly, yeast, two plants and E.coli. Tools for pathway analysis include Skypainter and Biomart. Pathway data can be exported in SBML and BioPAX formats. A description of Reactome has been published in Genome Biology and Nucleic Acids Research. Protein-protein interaction datasets, statistics and the editorial calendar are available. The Reactome team thanks users for their comments on the pathway analysis and pathway visualization tools. Click on contact to reach us, on editorial to contribute to Reactome content, and on subscribe to receive Reactome announcements. Please take note of our disclaimer.		January 15, 2010 Feedback Request - Target Species for Orthology Inference Reactome provides orthology-based pathway projections from human to other species. We are currently reviewing the list of target species. Please let us know if you would like to include a species that's not in the planned target species list. December 15, 2009 Version 31 Released Version 31 includes the new topics Metabolism of mRNA and Cell junction organization. Topics revised and updated with new events in this release include Transmembrane transport of small molecules (SLC-mediated transmembrane transport), Muscle contraction (Smooth muscle contraction), Hemostasis, Nuclear receptor transcription pathway, and Olfactory Signaling Pathway. JW Akkerman, is our external author in this release. L Freedman, L He, A Poole, M Rush, A Sonnenberg, D Tukey, L Vosshall, J Wilusz, and C Wu are our external reviewers. As part of the HUPO Proteomics Standards Initiative (PSI), we now annotate modified residues of proteins using MOD terms, and provide listings of protein-protein interactions in PSI-MITAB format.. Reactome data is now available in BioPAX level 3(release 1.0) and level 2 format. Reactome is now on Facebook, Twitter, and LinkedIn. More...

About Reactome

News and Notes

REACTOME is a free, online, open-source, curated pathway database encompassing many areas of human biology. Information is authored by expert biological researchers, maintained by the Reactome editorial staff and cross-referenced to the NCBI Entrez Gene, Ensembl and UniProt databases, the UCSC and HapMap Genome Browsers, the KEGG Compound and ChEBI small molecule databases, PubMed, and GO. The curated human data are used to infer orthologous events in 22 non-human species including mouse, rat, chicken, puffer fish, worm, fly, yeast, two plants and E.coli. Tools for pathway analysis include Skypainter and Biomart.

Pathway data can be exported in SBML and BioPAX formats.

A description of Reactome has been published in Genome Biology and Nucleic Acids Research.
Protein-protein interaction datasets, statistics and the editorial calendar are available. The Reactome team thanks users for their comments on the pathway analysis and pathway visualization tools.

Click on contact to reach us, on editorial to contribute to Reactome content, and on subscribe to receive Reactome announcements.

Please take note of our disclaimer.

January 15, 2010 Feedback Request - Target Species for Orthology Inference
Reactome provides orthology-based pathway projections from human to other species. We are currently reviewing the list of target species. Please let us know if you would like to include a species that's not in the planned target species list.
December 15, 2009 Version 31 Released
Version 31 includes the new topics Metabolism of mRNA and Cell junction organization. Topics revised and updated with new events in this release include Transmembrane transport of small molecules (SLC-mediated transmembrane transport), Muscle contraction (Smooth muscle contraction), Hemostasis, Nuclear receptor transcription pathway, and Olfactory Signaling Pathway.
JW Akkerman, is our external author in this release. L Freedman, L He, A Poole, M Rush, A Sonnenberg, D Tukey, L Vosshall, J Wilusz, and C Wu are our external reviewers.
As part of the HUPO Proteomics Standards Initiative (PSI), we now annotate modified residues of proteins using MOD terms, and provide listings of protein-protein interactions in PSI-MITAB format..
Reactome data is now available in BioPAX level 3(release 1.0) and level 2 format.
Reactome is now on Facebook, Twitter, and LinkedIn.
More...